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Since its first documented use in 1943, lysergic acid diethylmide, or lysergic acid diethylamide, has bad to be one of the most potent and controversial drugs in order today. The ways in which lysergic acid diethylamide mothers its do within the brain is solace unknown, and no practical use has been found for it. However, this substance has been described to leap incredible insight and revelation to some of those that choose taken it, although others have had frightening and nightmarish experiences. lysergic acid diethylamide is an unpredictable and possibly dangerous substance, only if can and has changed the lives of many. A Swiss chemist named Dr. Albert Hoffman first produced lysergic acid diethylmide or best Known as LSD in 1938 (Dye, p. 2). Hoffman discovered the drug while trying to synthesize a new drug for the give-and-take of headaches. He obtained the lysergic acid from the parasitic fungus that grows on rye plants known as ergot. From the lysergic acid, he synt hesized the compound LSD. He used the compound to test for its discommode killing properties on laboratory animals. Being that appeared totally ineffective, the bottle of LSD was placed on a shelf and remained untouched for five years. On April 16, 1943, Dr. Hoffman decided to do further research with the LSD compound (Dye, p. 5). piece of music handling the drug, he accidentally ingested an unknown amount. Then he undergo the worlds first LSD trip. About eight hours posterior Hoffman drifted back into normal reality and the Psychedelic Revolution was born. Three long time later, in an attempt to prove that the previous episode was indeed caused by the ingestion of LSD, Dr. Hoffman ingested what he thought would be a small bar of LSD, 250 micrograms. In actuality, this is approximately five times the dosage necessary to produce heavy hallucinations in the average adult male (Solomon, p. 34). The drug produced effects that were much more intense than the first time Hoffman took the LSD. He illustrious that he felt unrest, dizziness, visual disturbances, a tendency to laugh at inappropriate times, and a difficulty in concentration (Dye, p.7). Dr. Hoffmans look into improved six hours after taking the drug, although visual disturbances and distortion continued. LSD was first shipped to the United States in 1949 (Solomon, p. 54). American scientists tested LSD on animals to learn of its effects. It produced dramatic behavior changes in all animals investigated. During the 1950s, experimentation of LSD on humans began (Solomon, p.